Immunohistochemical detection of Glial Fibrillary Acidic Protein, by Munira B

By in2scienceuk Uncategorized

During my research placement at the Medical Research Centre for Developmental Neurobiology with Dr Tara Keck, I was able to take part in various experiments and techniques from electrophysiology to measure the potential difference and current of neurons, using computer software ‘Fiji’ to analyse neurons that are Green Fluorescent Protein (GFP) positive in inhibitory cells and immunohistochemistry […]

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Searching for genes involved in neurodegeneration, by Rebecca E

By in2scienceuk Uncategorized

The research my laboratory focused on was finding important proteins or eliminating genes that could affect neurodegeneration. One particular disease which is focused on is dentatorubral-pallidoluysian atrophy  (DRPLA). The mating scheme diagram you can see in the image below is a hypothetical one created as a practice for designing ones in the lab. My supervisor Catarina regularly designed the mating schemes for […]

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A placement in Developmental Neurobiology by Morgan M

By in2scienceuk Uncategorized

Morgan describes her time in the MRC Centre for Developmental Neurobiology at King’s College London. Things were more than busy on my first Wednesday whilst working at the lab for my work placement at the MRC Centre for Developmental Neurobiology at King’s College, not only was it my turn to work my way through the […]

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Polymerase Chain Reaction

By in2scienceuk Uncategorized

Continued from her previous post, Lucky tells us about her experience with using a fundamental technique in molecular biology – the polymerase chain reaction (PCR)… During my placement I had the opportunity to observe the isolation of RNA and the process of reverse transcription to get cDNA; with this I learnt how enzymes, for example […]

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Yeasts are not only used in baking bread!

By in2scienceuk Uncategorized

Over the two weeks spent in the laboratory I have learnt about how significant understanding and testing pathogens (particularly Candida albicans and Candida galbrata) is to preventing human fungal diseases being contracted. I spent time investigating the different strains of yeast at both a molecular level through polymerase chain reactions (PCR) which analysed the yeast strains […]

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