Searching for genes involved in neurodegeneration, by Rebecca E
The research my laboratory focused on was finding important proteins or eliminating genes that could affect neurodegeneration. One particular disease which is focused on is dentatorubral-pallidoluysian atrophy (DRPLA). The mating scheme diagram you can see in the image below is a hypothetical one created as a practice for designing ones in the lab. My supervisor Catarina regularly designed the mating schemes for flies so that she would be able to generate flies with certain genotypes to observe. It was amazing to find that some of the diagrams she had to make involved crossing the different stocks of flies 11 times, just to get the desired genotype.